What is Monkeypox? Monkeypox is a zoonotic disease caused by infection with the monkeypox virus. What are the clinical signs of monkeypox infection? 1. The incubation period is usually 6 to 13 days, but it can also be between 5 and 21 days; 2. Initial symptoms include fever, headache, swollen lymph nodes, severe fatigue, etc.; 3. After a few days of fever, it develops into a large rash on t...
What are the hormones fertility? When do I need to check? When is the right time to check? What's the point of each one? 1. Follicle-stimulating hormone (FSH) It is a glycoprotein hormone secreted by the pituitary gland, and its physiological role is mainly to promote the development and maturation of follicles and secrete estrogen. 2. Luteinizing hormone (LH) It is a glycoprotein hormon...
Platelet activation plays a crucial role in primary hemostasis, which is the initial step in the physiological repair mechanism to prevent further bleeding when blood vessel walls are damaged. Platelet activation involves three processes: platelet adhesion, aggregation, and secretion. These processes lead to the formation of a platelet plug at the site of vessel injury, which is essential for prim...
Thyroid function abnormalities primarily encompass two conditions: Hypothyroidism (commonly referred to as "hypothyroid") and Hyperthyroidism (commonly referred to as "hyperthyroid"). Thyroid function testing plays a vital role in early detection of thyroid diseases and is one of the essential components of a health-up. Thyroid function abnormalities can give rise to various health issues. ...
After understanding platelet activation function, this article will now introduce the clinical significance of platelet activation. Normal platelet activation and aggregation are necessary defense mechanisms that help with hemostasis and repair of damaged blood vessels. However, excessive activation can lead to thrombotic disorders. Modern clinical research has shown that many diseases, especially...
Cluster of Differentiation (CD Markers), as small proteins secreted by immune cells, play a key role in maintaining immune system stability and regulating pathological processes. It has a wide range of clinical applications, including auxiliary diagnosis, prognosis assessment, identification of infectious sources, early warning of cytokine storms, and monitoring of tumor immunity. In addition, the...
The bactericidal ability of HBP as well as the heparin-binding ability are related to its strong positive charge. HBP, as a chemotactic substance, can activate monocytes and macrophages, induce vascular leakage and tissue edema. Inactivating HBP blocks endothelial hyperosmocyte hyperpermeability caused by neutrophils. At present, HBP, as an acute phase protein, is an effective biomarker to assess ...
Infectious diseases are one of the common diseases in the emergency department, and the systemic inflammatory response syndrome caused by infection is the most fundamental pathophysiological change in sepsis. Due to the complexity of the systemic inflammatory response, there are no ideal diagnostic, stratification, prognostic tools, and effective treatment options. A number of studies have demonst...