World Stroke Day | "Wind" risk in platelet activation early warning
October 29 , 2024
World Stroke Day is observed on October 29 to underscore the serious nature and high rates of stroke, raise awareness of the prevention and treatment of the condition, and ensure better care and support for survivors.
Stroke and platelet function
Stroke refers to an acute cerebrovascular disease caused by the sudden rupture of blood vessels in the brain or the sudden interruption of blood flow to the brain. Hemorrhagic stroke, caused by a ruptured blood vessel in the brain, and ischemic stroke, caused by disruption of blood flow to the brain, are the two main types of stroke. Among them, ischemic stroke, also known as cerebral infarction, includes cerebral thrombosis and cerebral embolism, accounting for 85% of strokes.
Platelet activation is the main mechanism of thrombosis and atherosclerosis. Activated platelets interact with various leukocytes such as monocytes, neutrophils, dendritic cells, and lymphocytes to trigger cell-to-cell signal transduction, resulting in thrombosis and a large synthesis of inflammatory mediators, among which P-selectin and PAC-1 are sensitive indicators of platelet activation.
Resonance Energy Transfer (CRET)" independently developed by Poclight Biotechnology, Successfully developed and marketed platelet activating factor detection kit, which is dedicated to preoperative patient bleeding risk assessment, early warning of reinfarction during hospitalization, and monitoring the efficacy of antiplatelet drugs. The testing items include CD62P CLIA test Kit, activated CD61 (PAC-1), CD41 clia immunoassay Kit, CD61, CD42a, CD42b, CD45, etc., and the company will continue to develop and launch new testing items to meet clinical needs.
Benefits:
Reliable: Truly reflects the activation state in the body.
Fast: Quantitative test results as fast as 5 minutes.
Portable and minimalist: maintenance-free, one-step sample addition.
Quality assurance: Supporting quality control products, reliable and reassuring.