Detection principle: ELISA: Use enzyme-labeled antibodies or antigens to produce chromogenic products through enzyme catalysis, and then quantitatively analyze target molecules by measuring the optical density of the chromogenic products. CLIA: Directly detects the light produced by a chemiluminescent reaction, without the need for enzyme catalysis, and uses a chemiluminescent substr...
Chemiluminescence is a chemical reaction that produces light without heating. It is widely used to detect and analyze various substances, such as environmental pollutants, food additives, etc. CLIA (Chemiluminescence Immunoassay) is a highly sensitive analytical technology that combines the principles of immunoassay and chemiluminescence to detect specific molecules, such as disease ...
Cytokines are a general term for a class of small molecule polypeptides or glycoproteins with extensive biological activity synthesized and secreted by immune cells or some non-immune cells, which have the functions of regulating the body's immune function, mediating inflammatory responses, participating in tissue repair, and promoting wound healing. In the development of tumor diseases, cytokines...
01 Exhibition Overview The 76th Annual Meeting of Clinical Chemistry of United States and Clinical Laboratory Medicine Expo ADLM (formerly AACC) will be held from July 30 to August 1, 2024 at McCormick Place Convention Center in Chicago, United States. Founded in 1949, ADLM is the world's highest quality and largest annual event for clinical testing, showcasing cutting-edge medical technolog...
In the first two issues of popular science, the mainstream chemiluminescence technology in immunodiagnosis was introduced, and it was also understood that chemiluminescence is divided into homogeneous chemiluminescence and heterogeneous chemiluminescence according to whether separation and cleaning steps are required. Compared with the traditional heterogeneous immunoassay mode, homogeneous chemil...
Vitamin D is essential for children's health, especially in terms of growth and bone health. Measurement of 25-hydroxy vitamin D (25-OH VD) is the most reliable diagnostic standard for vitamin D levels. Vitamin D deficiency in children harms: ◎1.Lack of vitamin D may cause rickets, which is a disease characterized by softening and deformation of bones, which may lead to short stature and de...
Diagnostic evaluation of hypertension The initial laboratory test for hypertension should not only measure basic blood routine items, but also recommend the detection of glycosylated hemoglobin and high-sensitivity C-reactive protein. This is because people with high blood pressure need to rule out the presence of diabetes. Diabetes mellitus is a common cause of secondary hypertension such as rena...
Platelet activation plays a crucial role in primary hemostasis, which is the initial step in the physiological repair mechanism to prevent further bleeding when blood vessel walls are damaged. Platelet activation involves three processes: platelet adhesion, aggregation, and secretion. These processes lead to the formation of a platelet plug at the site of vessel injury, which is essential for prim...