Platelet activation plays a crucial role in primary hemostasis, which is the initial step in the physiological repair mechanism to prevent further bleeding when blood vessel walls are damaged. Platelet activation involves three processes: platelet adhesion, aggregation, and secretion. These processes lead to the formation of a platelet plug at the site of vessel injury, which is essential for prim...
After understanding platelet activation function, this article will now introduce the clinical significance of platelet activation. Normal platelet activation and aggregation are necessary defense mechanisms that help with hemostasis and repair of damaged blood vessels. However, excessive activation can lead to thrombotic disorders. Modern clinical research has shown that many diseases, especially...
September 13, 2024 is the 13th World Sepsis Day, and since the first World Spesis Day (WSD) was established in 2012, the global healthcare community and the public have been raising awareness of this serious and life-threatening disease year by year. On this day, we once again focused on sepsis, aiming to further raise public awareness of sepsis through scientific education and other activities, r...
1. New progress in luminescence: The number of manufacturers is gradually increasing The addition of new brands is bound to accelerate the clinical acceptance of luminescence detection cytokines. Differentiation began to emerge in the items From the perspective of the manufacturers that have been certified so far, the main items cover IL-1β, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-8, IL-10, TN...
Cluster of Differentiation (CD Markers), as small proteins secreted by immune cells, play a key role in maintaining immune system stability and regulating pathological processes. It has a wide range of clinical applications, including auxiliary diagnosis, prognosis assessment, identification of infectious sources, early warning of cytokine storms, and monitoring of tumor immunity. In addition, the...
B-type natriuretic peptide (BNP) and N-terminal B-type natriuretic peptide precursor (NT-proBNP) are biomarkers of cardiac function, as well as the preferred biomarkers for the diagnosis and differential diagnosis of heart failure, disease severity and prognosis assessment, and have been recommended as Level I by several clinical practice guidelines. BNP is mainly degraded in large blood ves...
In vitro diagnostic reagent stability refers to the ability of an in vitro diagnostic medical device to maintain its performance characteristics within the limits specified by the manufacturer, reflecting the product's ability to grow with In the process of storage, transportation and use of in vitro diagnostic reagents, various influencing factors such as temperature, humidity, light, repe...
Chemiluminescence immunoassay technology has long been well-known in the field of in vitro diagnostics! These include, direct chemiluminescence, electrochemiluminescence, enzymatic chemiluminescence, indirect chemiluminescence. So many types of luminescence use luminescent agents that are also very different!1. Acridine ester Direct chemiluminescence Acridine ester (AE) is a tricyclic organic...