1. What is KL-6? KL-6 is recognized as a valid indicator of lung injury and pulmonary fibrosis, and is expressed on the surface of type II alveolar epithelial cells, in normal lung tissue and terminal bronchiolar epithelial cells. It is expressed in very small amounts, and is enhanced in degenerative (proliferating, regenerating, or damaged) type II alveolar epithelial cells, which is directly rel...
In vitro diagnostics (IVD), refers to products and services that obtain clinical diagnostic information by testing human samples (various body fluids, cells, tissue samples, etc.) outside the human body, and then judge diseases or body functions. In vitro diagnostics is known as the "doctor's eye" in the medical field, and is an important part of modern laboratory medicine, and its clinical ...
The paramount importance of chemiluminescence technology—a mainstream technique in immunodiagnostics—in the field of In Vitro Diagnostics (IVD) is self-evident. However, in the current highly competitive environment, technological innovation remains the core competitiveness of enterprises. Breaking through the traditional barriers of chemiluminescence and forging new paths is the inevi...
Vitamin D is essential for children's health, especially in terms of growth and bone health. Measurement of 25-hydroxy vitamin D (25-OH VD) is the most reliable diagnostic standard for vitamin D levels. Vitamin D deficiency in children harms: ◎1.Lack of vitamin D may cause rickets, which is a disease characterized by softening and deformation of bones, which may lead to short stature and de...
Thyroid function abnormalities primarily encompass two conditions: Hypothyroidism (commonly referred to as "hypothyroid") and Hyperthyroidism (commonly referred to as "hyperthyroid"). Thyroid function testing plays a vital role in early detection of thyroid diseases and is one of the essential components of a health-up. Thyroid function abnormalities can give rise to various health issues. ...
After understanding platelet activation function, this article will now introduce the clinical significance of platelet activation. Normal platelet activation and aggregation are necessary defense mechanisms that help with hemostasis and repair of damaged blood vessels. However, excessive activation can lead to thrombotic disorders. Modern clinical research has shown that many diseases, especially...
Cluster of Differentiation (CD Markers), as small proteins secreted by immune cells, play a key role in maintaining immune system stability and regulating pathological processes. It has a wide range of clinical applications, including auxiliary diagnosis, prognosis assessment, identification of infectious sources, early warning of cytokine storms, and monitoring of tumor immunity. In addition, the...
The bactericidal ability of HBP as well as the heparin-binding ability are related to its strong positive charge. HBP, as a chemotactic substance, can activate monocytes and macrophages, induce vascular leakage and tissue edema. Inactivating HBP blocks endothelial hyperosmocyte hyperpermeability caused by neutrophils. At present, HBP, as an acute phase protein, is an effective biomarker to assess ...