After understanding platelet activation function, this article will now introduce the clinical significance of platelet activation. Normal platelet activation and aggregation are necessary defense mechanisms that help with hemostasis and repair of damaged blood vessels. However, excessive activation can lead to thrombotic disorders. Modern clinical research has shown that many diseases, especially...
Cluster of Differentiation (CD Markers), as small proteins secreted by immune cells, play a key role in maintaining immune system stability and regulating pathological processes. It has a wide range of clinical applications, including auxiliary diagnosis, prognosis assessment, identification of infectious sources, early warning of cytokine storms, and monitoring of tumor immunity. In addition, the...
The bactericidal ability of HBP as well as the heparin-binding ability are related to its strong positive charge. HBP, as a chemotactic substance, can activate monocytes and macrophages, induce vascular leakage and tissue edema. Inactivating HBP blocks endothelial hyperosmocyte hyperpermeability caused by neutrophils. At present, HBP, as an acute phase protein, is an effective biomarker to assess ...
Infectious diseases are one of the common diseases in the emergency department, and the systemic inflammatory response syndrome caused by infection is the most fundamental pathophysiological change in sepsis. Due to the complexity of the systemic inflammatory response, there are no ideal diagnostic, stratification, prognostic tools, and effective treatment options. A number of studies have demonst...
World Stroke Day is observed on October 29 to underscore the serious nature and high rates of stroke, raise awareness of the prevention and treatment of the condition, and ensure better care and support for survivors. Stroke and platelet function Stroke refers to an acute cerebrovascular disease caused by the sudden rupture of blood vessels in the brain or the sudden interruption of blood flo...