Coagulation Function vs. Platelet Function Coagulation function and platelet function are both related to blood clotting and hemostasis, but they operate through different mechanisms. In normal circumstances, the body maintains a dynamic balance between the coagulation and anticoagulation systems, which is crucial for preventing abnormal bleeding or thrombus formation. Imbalances in this equilibri...
September 13, 2024 is the 13th World Sepsis Day, and since the first World Spesis Day (WSD) was established in 2012, the global healthcare community and the public have been raising awareness of this serious and life-threatening disease year by year. On this day, we once again focused on sepsis, aiming to further raise public awareness of sepsis through scientific education and other activities, r...
Cluster of Differentiation (CD Markers), as small proteins secreted by immune cells, play a key role in maintaining immune system stability and regulating pathological processes. It has a wide range of clinical applications, including auxiliary diagnosis, prognosis assessment, identification of infectious sources, early warning of cytokine storms, and monitoring of tumor immunity. In addition, the...
World Heart Day was created by the World Heart Federation to inform people around the world that cardiovascular disease (CVD), including heart disease and stroke, is the leading cause of death in the world. This year's theme is " Heart and Action Integration ", which emphasizes the close connection between heart health and our daily behavior and reminds us to maintain and promote ...
The bactericidal ability of HBP as well as the heparin-binding ability are related to its strong positive charge. HBP, as a chemotactic substance, can activate monocytes and macrophages, induce vascular leakage and tissue edema. Inactivating HBP blocks endothelial hyperosmocyte hyperpermeability caused by neutrophils. At present, HBP, as an acute phase protein, is an effective biomarker to assess ...
B-type natriuretic peptide (BNP) and N-terminal B-type natriuretic peptide precursor (NT-proBNP) are biomarkers of cardiac function, as well as the preferred biomarkers for the diagnosis and differential diagnosis of heart failure, disease severity and prognosis assessment, and have been recommended as Level I by several clinical practice guidelines. BNP is mainly degraded in large blood ves...
In vitro diagnostic reagent stability refers to the ability of an in vitro diagnostic medical device to maintain its performance characteristics within the limits specified by the manufacturer, reflecting the product's ability to grow with In the process of storage, transportation and use of in vitro diagnostic reagents, various influencing factors such as temperature, humidity, light, repe...
Infectious diseases are one of the common diseases in the emergency department, and the systemic inflammatory response syndrome caused by infection is the most fundamental pathophysiological change in sepsis. Due to the complexity of the systemic inflammatory response, there are no ideal diagnostic, stratification, prognostic tools, and effective treatment options. A number of studies have demonst...