What is Tumor Microenvironment (TME)? The tumor microenvironment (TME) is a constantly changing framework intricately linked with cancer cells, largely influenced by their presence. Distinctive traits of the TME include irregular blood vessels, hypoxia, acidic pH levels outside cells, modifications in the extracellular matrix, and stromal components like cancer-associated fibroblasts, macrophages,...
1. Molecular detection Whether it is variable temperature PCR or isothermal amplification, fluorescence is the main detection method. After the luminescent group on the fluorescent probe is cut off, it is no longer in a quenched state and fluoresces under excitation. 2. Indirect immunofluorescence A more typical product is a self-exempt test In addition, this method is also used for the detection ...
1、What is Preeclampsia? Preeclampsia, is a hypertensive disorder of pregnancy that can cause systemic multi-organ damage to pregnant women, which is mainly manifested as hypertension and high protein in the urine (systolic blood pressure ≥ 140mmHg, diastolic blood pressure ≥90mmHg) and high protein in the urine (0.3g/24h). It is one of the leading causes of maternal death, preterm birth, neo...
1. Understanding Thyroid Function A normal thyroid gland is important for the body's growth, behavior, and psychological and neurological development. The main function of the thyroid gland is to produce, store, and secrete thyroid hormones (TH), including thyroxine (T4) and triiodothyronine (T3), and is regulated by the hypothalamic-pituitary-thyroid axis. TH has a role in regulating mood, brain ...
1. How can vitamin D deficiency impact overall well-being? ♣ Vitamin D deficiency rickets (nutritional rickets) Vitamin D deficiency during childhood can lead to rickets in children, causing growth delays and skeletal deformities. Essentially, Vitamin D deficiency rickets is a form of osteomalacia. The onset of this condition is gradual, often occurring in infants between the ages of 3 month...
♣ Vitamin B12, also known as adenosylcobalamin or cyanocobalamin, is an essential water-soluble vitamin. It plays a key role in the body, including maintaining the normal function of the nervous system, promoting the production of red blood cells, and supporting DNA synthesis. The main difference between active B12 and B12 lies in their chemical forms and bioavailability. 1. Chemical form: B...
1. The necessity of developing cytokines in the Department of Hematology In the treatment of some diseases, such as bloodstream infection, hemophagocytic syndrome (HLH), leukemia, sepsis, etc., the inflammatory response status of patients is mostly detected, so cytokine detection plays an important role in the selection, adjustment and prognosis evaluation of treatment regimens. ⇔Hemophagocyt...
Cytokines are a general term for a class of small molecule polypeptides or glycoproteins with extensive biological activity synthesized and secreted by immune cells or some non-immune cells, which have the functions of regulating the body's immune function, mediating inflammatory responses, participating in tissue repair, and promoting wound healing. In the development of tumor diseases, cytokines...