Platelet activation plays a crucial role in primary hemostasis, which is the initial step in the physiological repair mechanism to prevent further bleeding when blood vessel walls are damaged. Platelet activation involves three processes: platelet adhesion, aggregation, and secretion. These processes lead to the formation of a platelet plug at the site of vessel injury, which is essential for prim...
Thyroid function abnormalities primarily encompass two conditions: Hypothyroidism (commonly referred to as "hypothyroid") and Hyperthyroidism (commonly referred to as "hyperthyroid"). Thyroid function testing plays a vital role in early detection of thyroid diseases and is one of the essential components of a health-up. Thyroid function abnormalities can give rise to various health issues. ...
Coagulation Function vs. Platelet Function Coagulation function and platelet function are both related to blood clotting and hemostasis, but they operate through different mechanisms. In normal circumstances, the body maintains a dynamic balance between the coagulation and anticoagulation systems, which is crucial for preventing abnormal bleeding or thrombus formation. Imbalances in this equilibri...
September 13, 2024 is the 13th World Sepsis Day, and since the first World Spesis Day (WSD) was established in 2012, the global healthcare community and the public have been raising awareness of this serious and life-threatening disease year by year. On this day, we once again focused on sepsis, aiming to further raise public awareness of sepsis through scientific education and other activities, r...
1. New progress in luminescence: The number of manufacturers is gradually increasing The addition of new brands is bound to accelerate the clinical acceptance of luminescence detection cytokines. Differentiation began to emerge in the items From the perspective of the manufacturers that have been certified so far, the main items cover IL-1β, IL-2, IL-2R, IL-4, IL-5, IL-6, IL-8, IL-10, TN...
Cluster of Differentiation (CD Markers), as small proteins secreted by immune cells, play a key role in maintaining immune system stability and regulating pathological processes. It has a wide range of clinical applications, including auxiliary diagnosis, prognosis assessment, identification of infectious sources, early warning of cytokine storms, and monitoring of tumor immunity. In addition, the...
The bactericidal ability of HBP as well as the heparin-binding ability are related to its strong positive charge. HBP, as a chemotactic substance, can activate monocytes and macrophages, induce vascular leakage and tissue edema. Inactivating HBP blocks endothelial hyperosmocyte hyperpermeability caused by neutrophils. At present, HBP, as an acute phase protein, is an effective biomarker to assess ...
B-type natriuretic peptide (BNP) and N-terminal B-type natriuretic peptide precursor (NT-proBNP) are biomarkers of cardiac function, as well as the preferred biomarkers for the diagnosis and differential diagnosis of heart failure, disease severity and prognosis assessment, and have been recommended as Level I by several clinical practice guidelines. BNP is mainly degraded in large blood ves...