Poclight: Breaking Out of the involution

I. Chemiluminescence: Escalating Innovation Leads to Dilemma

In the field of chemiluminescence, internal competition is intensifying, leaving the industry in a dilemma. With continuous technological advancements and heightened market competition, companies and research institutions face immense pressure and challenges. The causes of internal competition in chemiluminescence analysis are as follows:

Ø Previously heavily favored by capital, but market performance fell short of expectations, leading to a gradual loss of enthusiasm from investors and the idea of sustained investment.

Ø Market demand for increased automation of equipment and continuous price reductions, resulting in increased costs for companies. This increase the production costs coupled with reduced funding sources leaves them in a dilemma.

Ø Rapid advancement in collective procurement and transparent profits make it difficult to reduce costs, leaving companies with the choice to either continue internal competition or gradually exit the market.

Ø High instrument costs result in sample waste after penetrating the market, jeopardizing the benefits of market penetration.

Ø Although multi-channel single-person chemiluminescence instruments solve instrument cost issues, reagents require refrigerated storage and transportation. Fluctuations in end-user consumption sometimes result in distribution challenges for distributors, occasionally leading to situations where transportation costs exceed reagent costs.

Ø Chemiluminescence requires certain skills for detection operations. The gap between operators in the third world market sometimes lead to inaccurate analysis and control of test results, while complex equipment setups increase post-sales pressure.

II. Breaking Involution: Only Through Innovation

The defeat of the carriage was never achieved by a better carriage, but by the application of newer technologies, such as steam cars. Technological innovation is the core competitiveness. The development of immunoassay testing is a story of innovative development. Starting from 1960, immunoassay diagnostic technology has continuously progress from the earliest radioimmunoassay to colloidal gold, enzyme-linked immunosorbent assay (ELISA), and chemiluminescence technologies, meeting clinical diagnostic needs.

III. Poclight Homogeneous CLIA- Breaking the Involution

Poclight's CRET (Chemiluminescence Resonance Energy Transfer) technology achieves homogeneous chemiluminescence. Unlike traditional magnetic particles, CRET extinguishes excess luminescence, enabling separation-free and washing-free processes. Traditional magnetic particles require the removal of excess luminescent material.

Homogeneous CLIA vs. MPCLIA

Ø No magnetic beads lower the cost which aligns well with the current situation.

Ø Separation-free and washing-free: Magnetic separation and washing increase the size and structure of the instrument, leading to increased costs. Homogeneous instruments are simpler and maintenance-free.

Ø Lyophilized reagents, low transportation costs: Because it is homogeneous, the reagent composition is relatively simple, enabling single-dose packaging without the need for cold chain transportation, reducing transportation costs.

In addition to the above advantages, homogeneous CLIA offers better repeatability due to no separation washing and no loss of luminescent signals. The detection process requires no mixing, resulting in high sensitivity. There is no need for encapsulation fixation, no spatial hindrance effect, no non-specific binding, and stable performance, among many other advantages.

IV. Industry Outlook

Homogeneous CLIA has many characteristics such as single-item testing, flexibility, free combination, fast speed, short time to the first result (600 tests per hour), quantitative detection results, no specific interference, unaffected by environmental temperature, no interference in single-item testing, no encoded microspheres, stable performance, low cost, no cleaning workstations for instruments, fast speed, low instrument cost, and high single-machine benefits. In the future, Poclight's homogeneous CLIA will undoubtedly become the new favorite of the capital market.